Metabolomics Reveals Target and Off-Target Toxicities of a Model Organophosphate Pesticide to Roach (Rutilus rutilus): Implications for Biomonitoring

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Metabolomics Reveals Target and Off-Target Toxicities of a Model Organophosphate Pesticide to Roach (Rutilus rutilus): Implications for Biomonitoring

The ability of targeted and nontargeted metabolomics to discover chronic ecotoxicological effects is largely unexplored. Fenitrothion, an organophosphate pesticide, is categorized as a "red list" pollutant, being particularly hazardous to aquatic life. It acts primarily as a cholinesterase inhibitor, but evidence suggests it can also act as an androgen receptor antagonist. Whole-organism fenitr...

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Sexual ornamentation, androgens and papillomatosis in male roach (Rutilus rutilus)

According to the immunocompetence handicap hypothesis, males with attractive sexual ornamentation are more handicapped than their less ornamented rivals because of the immunosuppressive androgens required for the production of secondary sexual characters. Here we studied the predictions of the hypothesis in a wild cyprinid fish, the roach (Rutilus rutilus). We assayed (1) sexual ornamentation (...

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Intraoligochaete development of Myxobolus intimus (Myxosporea: Myxobolidae), a gill myxosporean of the roach (Rutilus rutilus).

The infection with Myxobolus intimus Zaika, 1965 in the gills of the roach Rutilus rutilus (L.) from Lake Balaton was recorded in 28 out of the 39 fish examined. Developing and mature plasmodia were detected on the gills exclusively in the spring. The Myxobolus intimus infection was found only in 2- to 3-year-old fish. In histological sections, young plasmodia were found in capillaries of the s...

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Extinction risk of exploited wild roach (Rutilus rutilus) populations due to chemical feminization.

A model that assesses risks posed by feminization to wild populations of roach was developed. A population life table matrix model that considered both sexes and a newly developed fertility kinetic function was applied to calculate the intrinsic population growth rate (lambda) of roach populations where males had been feminized. The maximum sustainable yield (MSY) was used to quantify the effec...

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Association between environmental stress and epidermal papillomatosis of roach Rutilus rutilus.

We studied the association between environmental stress and epidermal papillomatosis of roach Rutilus rutilus L. in Finnish waters using a 'matched pairs' design. Populations impacted by industrial and/or sewage effluents were compared to reference populations from pristine sites. We examined both the prevalence (proportion of diseased fish) and intensity (number of scales covered by tumors) of...

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ژورنال

عنوان ژورنال: Environmental Science & Technology

سال: 2011

ISSN: 0013-936X,1520-5851

DOI: 10.1021/es103814d